2025 Spring Miami Pediatric Nephrology Seminar : simplebooklet.com

FRIDAY MARCH 21ALL OF THE LECTURES WILL BE HELD IN JASMINEJoint PNRC Miami Seminar Lunch(Monroe/Tuttle Ballroom)....................................12:00PM-1:00PMFoundation Sponsor (Christine Sethna, MD, EdM-The Role ofComplement in FSGS)Welcome: Seminar Co-Chairs Marissa DeFreitas &Chryso Katsoufis and Chair, Department ofPediatrics Dr. Glenn Flores, MD, FAAPEmerging Therapeutic Targets &Pathophysiologic Principles 1:00-3:30PM Tubulo-glomerular feedback & SGLT2 inhibitors 1. 2. Therapeutic options for pediatric cystic kidney disease 3. Fun with Sodium Two 4. Gene therapies for heritable kidney disease 5. Effects of an iron-based binder on FGF23 levels in children with CKDPanel DiscussionModerators: Rick J. Kaskel MD, PHDJohn D. Mahan MD1. Chryso P. Katsoufis MD2. Melissa Cadnapaphornchai MD3. Larry Greenbaum MD, PhD4. Friedhelm Hildebrandt MD5. Isidro B. Salusky MD Break + Exhibitors..........................................................3:30-3:45PM (Upper & Lower Promenade)Advances in Clinical Practice from theGlomerulus to the Tubule 3:45-5:45PM Advocacy in neonatal nephrology care1. 2. Tubulo-interstitial kidney disease in children 3. Pro Con: Evaluation & follow up of persistent microscopic hematuria- the interventionist 4. Pro Con: Evaluation & follow up of persistent microscopic hematuria-the conservativePanel DiscussionModerators: Alex R. Constantinescu MDEwa Elenberg MD, MEd Posters + Exhibitors + Light Reception.....5:45-6:30PM (Upper & Lower Promenade)1. Kimberly J. Reidy MD2. Darcy K. Weidemann MD, MHS3. John D. Mahan MD4. Myda Khalid MD02

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SATURDAY MARCH 22ALL OF THE LECTURES WILL BE HELD IN JASMINE03Breakfast (on your own in the hotel) ......................6:30-7:45AM *All Attendees may charge their room up to $20 for breakfast (breakfast purchased outside of the hotel will not be reimbursed)Growing Concerns: Pediatric Hypertension andIts Impact on Cardiovascular Health 8:00-10:00AMMechanisms of end organ dysfunction in pediatrichypertension1.Nocturnal hypertension: cardiac and kidney outcomes2.Clinical impact of diastolic dysfunction in pediatricCKD + FGF 233.Non-pharmacologic therapy of hypertension:Anything new?4.Panel DiscussionModerators: Julie R. Ingelfinger MDJoseph T. Flynn MD, MS1. Ikuyo Yamaguchi MD, PhD2. Joseph T. Flynn MD, MS3. Wacharee Seeherunvong MD4. Christine Sethna MD, EdM Break + Exhibitors + Posters..................................10:00-10:15AM (Upper & Lower Promenade)Exploring Developmental Nephrology and ItsImpact on Kidney Health 10:15AM-12:15PMUnderstanding perinatal risk of future cardio-renaldisease1.Implementation of kidney health screening after NICUdischarge2.Promoting postnatal nephrogenesis-A window ofopportunity3.VUR: 10+ Years After RIVUR4.Panel DiscussionModerators: Keia Sanderson MD, MSCRCarolyn Abitbol, MD1. Keia Sanderson MD, MSCR2. Michelle Starr MD, MPH3. Marissa DeFreitas MD, MS4. Tej Mattoo MD Lunch with the Professors & Trainees (invitation only) Lunch- all attendees(Monroe/Tuttle Ballroom)........12:15- 1:15PM Diamond Sponsor (Michael Somers, MD- “OXLUMO® (lumasiran)for the Treatment of Primary Hyperoxaluria (PH1): Case Studies”)

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04SATURDAY MARCH 22ALL OF THE LECTURES WILL BE HELD IN JASMINEUnraveling Pediatric Glomerular Diseases 1:15-3:15PMTherapeutic targets in nephrotic syndrome:Circulating factors1.Therapeutic targets in nephrotic syndrome:Cellular-level targets2.Glomerular Disease: Engaging our Patients3.Updated guidelines for the management of lupusnephritis4.Panel DiscussionModerators: William E. Smoyer MDFriedhelm Hildebrandt MD1. Matthew Sampson MD, MS Stefano Da Sacco, PhD2. Gabriel Cara-Fuentes MD, PhD3. Chia-shi Wang MD, MSc4. Yelena Drexler MD Break +Exhibitors + Posters.........................................3:15-3:30PM (Upper & Lower Promenade)Young Investigator’s Showcase 3:30-5:30pm Oral Presentations (5) + Poster Exhibition + Awards Dysregulated glomerular S1P metabolism contributesto glomerular injury1. Acute Kidney Injury Associated with CidofovirExposure in Immunocompromised Pediatric Patients 2. Impact of Social Determinants of Health on the HealthOutcomes of Children with Chronic Kidney Disease(CKD)3. A comparison of demographics and outcomes ofkidney disease in adolescents and young adults withend stage kidney disease: A USRDS registry study4. Pediatric Nephrology Simulation-Based Curriculum:Hypotension during Hemodialysis5.Moderators: Larry Greenbaum MD, PhDGastón Zilleruelo MD1. Antonio Fontanella2. Rayan Terkawi3. Christel Wekon-Kemeni4. Jieji Hu5. Rajavee Panchal Social Reception.............................................................5:30-7:30PM(Upper & Lower Promenade)

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SUNDAY MARCH 23ALL OF THE LECTURES WILL BE HELD IN JASMINE Breakfast (on your own in the hotel) .....................6:30-7:45AM *All Attendees may charge their room up to $20 for breakfast (breakfast purchased outside of the hotel will not be reimbursed)New Horizons in Pediatric Kidney Transplantation 8:00-10:30AM Diagnosis and management of acute rejection in 1. pediatric kidney 2. Donor selection in pediatric kidney transplantation: Medical perspective 3. Donor selection in pediatric kidney transplantation: Surgical perspective 4. Minimizing the risk of PTLD in the current era 5. Transition of Renal Transplant from Pediatric to Adult CarePanel DiscussionModerators: George Burke III MDJayanthi Chandar MD, MS1. Namrata G. Jain MD2. Vaka Sigurjonsdottir MD3. Mahmoud Morsi MD4. Vikas R. Dharnidharka MD, MPH5. Rupesh Raina MDBreak +Exhibitor + Posters......................................10:30-10:45AM(Upper & Lower Promenade)Global Session: Uniting for a Brighter Future inPediatric Nephrology * Dedication to Pat Brophy 10:45AM-12:45PM Progress in the management of pediatric AKI in low 1. resource countries 2. APOL1 Variants and CKD in West Africans 3. Updated international pediatric peritonitis guidelines 4. Psychosocial challenges for children and young people requiring kidney replacement therapyPanel DiscussionModerators: Bradley A. Warady MDRupesh Raina MD1. Melvin Bonilla-Félix MD2. Titilayo Ilori MD, MSc3. Francisco Cano MD4. Matko Marlais MBBS, MSC Announcements & Concluding Remarks.......................12:45PM05

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Marissa DeFreitas, MD, MSChryso P. Katsoufis, MD06CONFERENCE DETAILSCOURSE DESCRIPTION HISTORYPROGRAMDIRECTORSThe Miami Pediatric Nephrology Seminarwas founded by Jose` Strauss, MD in 1974with over 50 years of impact within thepediatric nephrology community.The Miami Pediatric Nephrology Seminar is aunique gathering of pediatric and adultnephrologists, pediatricians, internists,general practitioners, renal pathologists,neonatologists, pediatric urologists,transplant surgeons, nurses, nutritionists,and allied health professionals from all overthe United States and the world sponsoredby the University of Miami, Leonard MillerSchool of Medicine and Holtz Children’sHospital at Jackson Memorial Hospital. Thecontent is basic, the approach is clinical.Conceptual and practical problems arefeatured in a balance of formalpresentations followed by informaldiscussions. Topics covered relate researchadvances to the understanding ofmechanisms of renal disease, pathologicalexpressions and clinical diagnosis andmanagement. All registrants haveopportunities to be involved in a dynamicexchange of information, experience, andinsight.ACCREDITATIONThis activity has been planned andimplemented in accordance with theaccreditation requirements and policies ofthe Accreditation Council for ContinuingMedical Education (ACCME) through thejoint providership of the University of MiamiLeonard M. Miller School of Medicine andPediatric Nephrology Research Consortium.The University of Miami Leonard M. MillerSchool of Medicine is accredited by theACCME to provide continuing medicaleducation for physicians.CREDITDESIGNATIONThe University of Miami Leonard M. MillerSchool of Medicine designates this liveactivity for a maximum of 16.25 AMA PRACategory 1 Credit™. Physicians should claimonly credit commensurate with the extentof their participation in the activity.

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08CONFERENCELEARNING OBJECTIVESUpon completion of the course, attendees will be able to:Define the various etiologies and physiologic conditions relating to thesesubjects, select appropriate diagnostic procedures.Understand that which may occur as a result of the disease process or treatmentand indicate appropriate therapy.Do basic or clinical research focused on pediatric nephrology challenges and willbe stimulated by those knowledgeable about research issues and will beinformed about support resources.Identify future research directions and new approaches and technologies thatwill eventually lead to a better understanding of these conditions and improvedtreatment prevention strategies. Recognize and contact the faculty who will serve as role models for futuregenerations of Pediatric Nephrologists and serve to stimulate interest in this fieldas a career choice.CONFERENCE DETAILSCarolyn Abitbol, MD Professor of Pediatrics, Division Chief, Division ofPediatric Nephrology, University of Miami Miller School ofMedicine (UMMSM) George Burke III, MD Professor of Surgery, Division of Transplant Surgery, Miami Transplant Institute, UMMSM Jayanthi Chandar, MD, MS Professor of Clinical Pediatrics, Medical DirectorPediatric Kidney Transplant, Division of PediatricNephrology, UMMSM Marissa DeFreitas, MD, MSAssociate Professor of Clinical Pediatrics, AssociateFellowship Program Director, Division of PediatricNephrology, UMMSM: Co-Chair Pediatric NephrologySeminarYelena Drexler, MDAssistant Professor, Division of Nephrology andHypertension, Director, University of Miami AutosomalDominant Polycystic Kidney Disease Clinic, UMMSMMichael Freundlich, MD Professor Emeritus of Clinical Pediatrics, UMMSM Chryso P. Katsoufis, MD Associate Professor of Clinical Pediatrics, Medical Director of Pediatric Dialysis, Division ofPediatric Nephrology, UMMSM; Co-Chair PediatricNephrology SeminarMahmoud Morsi, MD Associate Professor, Department of Surgery,UMMSM Wacharee Seeherunvong, MD Associate Professor of Clinical Pediatrics,Fellowship Program Director, Division of PediatricNephrology, UMMSMVaka Sigurjonsdottir, MDAssistant Professor of Clinical Pediatrics, Division of Pediatric Nephrology, UMMSMGastón E. Zilleruelo, MDProfessor Emeritus of Pediatrics, UMMSMLOCAL FACULTY

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09GUEST FACULTYMelvin Bonilla-Félix, MD Professor, Section of Nephrology and Hypertension,Department Pediatrics, University of Puerto RicoSchool of Medicine, Santurce, Puerto Rico Melissa Cadnapaphornchai, MD Professor of Clinical Pediatrics, Division of Nephrologyat Children’s Hospital of Philadelphia, Philadelphia, PA Francisco Cano, MD Professor Titular, Departamento Pediatria y CirugiaInfantil Oriente Facultad de Medicina Unversidad deChile, Coordinador Programa Dialsis PeritonealUnidad de Nefrologia Infantil, Servicio de PediatriaHospital Luis Calvo Mackenna, Santiago, ChilePresident ALANEPEGabriel Cara-Fuentes, MD, PhDAssistant Professor, Ohio State University, PediatricNephrology, Nationwide Children’s Hospital,Columbus, OHAlex R. Constantinescu, MDMedical Director of the Pediatric Nephrology and Hypertension, Pediatric Dialysis and Pediatric Kidney Transplantation Programs, Joe DiMaggio Children’s Hospital, Ft. Lauderdale, FLStefano Da Sacco, PhDAssistant Professor of UrologyChildren’s Hospital Los Angeles and Keck School ofMedicine - University of Southern CaliforniaLos Angeles, CAVikas R. Dharnidharka, MD, MPHHenry Rutgers Professor, Chair, Department ofPediatrics, Robert Wood Johnson Medical School atRutgers University, Pediatrician-in-Chief of Bristol-Myers Squibb Children’s Hospital, New Brunswick, NJMaria E. Diaz-Gonzalez de Ferris,MD, MPH, PhDProfessor, Director of Healthcare Transition Program, UNC School of Medicine, Chapel Hill, NCEwa Elenberg, MD, MEdProfessor, Division of Pediatric Nephrology, BaylorCollege of Medicine, Texas Children’s Hospital,Houston TXJoseph T. Flynn MD, MSProfessor of Pediatrics, University of Washington,Seattle Children’s Hospital, Seattle WA; Editor-in-Chief, Pediatric Nephrology Larry A. Greenbaum, MD, PhD, FAAP Marcus Professor of Pediatrics, Chief, Division ofPediatric Nephrology, Emory School of Medicine andChildren’s Healthcare of Atlanta, Director, Children’sPhysician Group, Atlanta, GA Friedhelm Hildebrandt, MD William E. Harmon Professor of Pediatrics, HarvardMedical School, Chief, Division of Nephrology,Boston Children’s Hospital, Boston, MA Titilayo Ilori, MD, MSc Assistant Professor, Boston University Chobanian &Avedisian School of Medicine, Boston, MAJulie R. Ingelfinger, MDProfessor of Pediatrics, Harvard Medical School,Senior Consultant in Pediatric Nephrology,Massachusetts General Hospital for Children,Boston, MA; Deputy Editor, The New England Journalof MedicineNamrata G. Jain, MDAssociate Professor, Medical Director PediatricKidney Transplant, Hackensack University MedicalCenter, Joseph M. Sanzari Children’s Hospital,Hackensack NJRick J. Kaskel, MD, PhD, FAAP, FASNChief Emeritus, Nephrology, Professor of PediatricsChildren’s Hospital at Montefiore, Division ofPediatric Nephrology, Bronx, NY

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GUEST FACULTY10Myda Khalid, MDAssociate Professor of Clinical Pediatrics, IndianaUniversity School of Medicine, Program DirectorPediatric Nephrology Fellowship Program, ClinicalResearch Program Director, Riley Hospital forChildren, Indianapolis, INJohn D. Mahan, MDProfessor, Department of Pediatrics, The Ohio StateUniversity College of Medicine, Director, NCH Centerfor Faculty Development, Associate Director,Pediatric Nephrology Fellowship Program, PediatricNephrology and Hypertension Division NationwideChildren’s Hospital, Columbus, OHMatko Marlais, MBBS, MSC, FRCPCH Consultant Paediatric Nephrology, Specialty Lead forPaediatric Nephrology, Associate Medical Director,Great Ormond Street Hospital for Children, LondonUnited Kingdom Tej Mattoo, MD, DCH, FRCP, FAAP Professor of Pediatrics, Vice Chair Department ofPediatrics, Pediatric Nephrology, Wayne StateUniversity School of Medicine, Detroit, MI; Chiefeditor, International Journal of Nephrology Rupesh Raina, MDAdult-Pediatric Kidney Disease/Hypertension,Professor of Medicine and Professor of Pediatrics,AGMC, Cleveland Clinic, Cleveland OH, Staff MedicalResearch, Rebecca D. Considine Research Insititute,Staff at Akron Children’s Hospital, Akron, OH, Councilfor Faculty of Internal Medicine, M-4 Director-College of Medicine Office of the Dean and MedicalEducation at Northeast Ohio Medical University,Rootstown, OHKimberly J. Reidy, MDChief, Division of Pediatric Nephrology, Associate Professor, Pediatric Nephrology,Children’s Hospital at Montefiore, Albert EinsteinCollege of Medicine, Bronx, NYMatthew Sampson, MD, MSAssociate Professor of Pediatrics, Harvard MedicalSchool, Division of Nephrology, Boston Children’sHospital, Boston, MAIsidro B. Salusky, MDDistinguished Professor of Pediatrics, David GeffenSchool of Medicine, UCLA, Chief of PediatricNephrology, Director of the Pediatric Dialysis Program,Los Angeles, CAKeia Sanderson, MD, MSCRAssistant Professor of Medicine and Pediatrics, Directorof Pediatric Dialysis, Division of Nephrology andHypertension, UNC School of Medicine, Chapel Hill, NCChristine Sethna, MD, EdM Division Director, Pediatric Nephrology, Director ofPediatric Fellowships, Cohen Children’s Medical Center,Associate Professor, Zucker School of Medicine atHofstra/Northwell, Feinstein Institutes for MedicalResearch, Queens, NY William E. Smoyer, MD C. Robert Kidder Chair Vice President, Clinical andTranslational Research, Director Center for Clinical andTranslational Research, The Research Institute atNationwide Children’s Hospital, Columbus, OH Michelle Starr, MD, MPH Assistant Professor of Pediatrics, Pediatric Nephrology,Indiana University School of Medicine, Indianapolis, INChia-shi Wang, MD, MScAssociate Professor of Pediatrics, Division of PediatricNephrology, Emory School of Medicine and Children’sHealthcare of Atlanta, Atlanta, GABradley A. Warady, MDProfessor of Pediatrics, University of Missouri-KansasCity School of Medicine, McLaughlin Family EndowedChair in Nephrology, Division Director, PediatricNephrology, Director, Dialysis and Transplantation,Kansas City, MO Darcy K. Weidemann, MD, MHSAssociate Professor of Pediatrics, University of Missouri-Kansas City School of Medicine, Children’s MercyHosptial, Kansas City, MO Ikuyo Yamaguchi, MD, PhDAssociate Professor, Division Chief of PediatricNephrology at Oklahoma University College of Medicine,Oklahoma Children’s Hospital, Oklahoma City, OK

2025 Spring Miami Pediatric Nephrology Seminar

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